Determination of Tedizolid in Bacterial Growth Medium Mueller-Hinton Broth by High-Performance Liquid Chromatography and Its Application to an In Vitro Study in the Hollow-Fiber Infection Model

Pharmacokinetic/pharmacodynamic (PKPD) studies of anti-infectives are frequently performed in in vitro infection models where accurate quantification of antibiotic concentrations in bacterial growth media is crucial to establish PK/PD relationships. Here, a sensitive and rapid high-performance liqui...

Full description

Bibliographic Details

Published in:	Separations
Main Authors:	Khalid Iqbal, Aliki Milioudi, Elena Haro Martínez, Sebastian Georg Wicha
Format:	Article
Language:	English
Published:	MDPI AG 2021-09-01
Subjects:	tedizolid HPLC Mueller-Hinton broth in vitro infection models
Online Access:	https://www.mdpi.com/2297-8739/8/9/141