Differential splicing choices made by neurons and astrocytes and their importance when investigating signal-dependent alternative splicing in neural cells

A variety of proteins can be encoded by a single gene via the differential splicing of exons. In neurons this form of alternative splicing can be controlled by activity-dependent calcium signaling, leading to the properties of proteins being altered, including ion channels, neurotransmitter receptor...

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Bibliographic Details

Published in:	Frontiers in Molecular Neuroscience
Main Authors:	Paul S. Baxter, Owen Dando, Giles E. Hardingham
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-07-01
Subjects:	neurexin alternative splicing epigenetics excitotoxicity astrocyte-specificity
Online Access:	https://www.frontiersin.org/articles/10.3389/fnmol.2023.1214439/full