Alpha-synuclein oligomers - neurotoxic molecules in Parkinson’s disease and other Lewy body disorders

Adverse intra- and extracellular effects of toxic α-synuclein are believed to be central to the pathogenesis in Parkinson’s disease and other disorders with Lewy body pathology in the nervous system. One of the physiological roles of α-synuclein relates to the regulation of neurotransmitter release...

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Bibliographic Details

Published in:	Frontiers in Neuroscience
Main Author:	Martin Ingelsson
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-09-01
Subjects:	Lewy Body Disease Therapeutics biomarker Toxicity propagation alpha-synuclein oligomers
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00408/full