Efficacy and safety of neoadjuvant PD-1 inhibitors or PD-L1 inhibitors combined with chemoradiotherapy for locally advanced rectal cancer: a systematic review and meta-analysis

BackgroundThe objective of this meta-analysis was to assess the effectiveness and safety of neoadjuvant PD-1/L1 inhibitors plus chemoradiotherapy(CRT) for locally advanced rectal cancer (LARC).Materials and MethodsDatabases including PubMed, Embase, Cochrane Library and Web of Science were examined...

詳細記述

書誌詳細

出版年:	Frontiers in Pharmacology
主要な著者:	Jiaojiao Yu, Zhijing Wang, Mingxu Li, Hua Zhu, Xiaoxia Tang, Ke Luan, Yinhuan Zhi, Shan Yin, Yuanqi Su, Jingyan Long, Qubo He, Jieru Quan, Chenchen Li
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2025-05-01
主題:	PD-1 inhibitor programmed cell death protein 1 inhibitor programmed death-ligand 1 inhibitor rectal cancer neoadjuvant chemoradiotherapy
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1570467/full