Identification and validation of ferroptosis-related biomarkers in intervertebral disc degeneration

IntroductionFerroptosis plays a significant role in intervertebral disc degeneration (IDD). Understanding the key genes regulating ferroptosis in IDD could reveal fundamental mechanisms of the disease, potentially leading to new diagnostic and therapeutic targets.MethodsPublic datasets (GSE23130 and...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Chenglong Li, Chengshuo Fei, Shiyong Le, Zhongming Lai, Bo Yan, Liang Wang, Zhongmin Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-09-01
Subjects:	intervertebral disc degeneration ferroptosis bioinformatics analysis immune cell infiltration single-cell RNA sequencing
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2024.1416345/full