Lipopolymers as the Basis of Non-Viral Delivery of Therapeutic siRNA Nanoparticles in a Leukemia (MOLM-13) Model

Small interfering RNA (siRNA) therapy in acute myeloid leukemia (AML) is a promising strategy as the siRNA molecule can specifically target proteins involved in abnormal cell proliferation. The development of a clinically applicable method for delivering siRNA molecules is imperative due to the chal...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Panadda Yotsomnuk, Amarnath Praphakar Rajendran, Daniel Nisakar Meenakshi Sundaram, Luis Carlos Morales, Cezary Kucharski, Mohammad Nasrullah, Wanwisa Skolpap, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Hasan Uludağ
Format:	Article
Language:	English
Published:	MDPI AG 2025-01-01
Subjects:	lipopolymers siRNA therapy nanoparticle siRNA polyplex MOLM-13 FLT3
Online Access:	https://www.mdpi.com/2218-273X/15/1/115