Constructing a mitochondrial-related genes model based on machine learning for predicting the prognosis and therapeutic effect in colorectal cancer

Abstract The role of mitochondria in tumorigenesis and progression is has been increasingly demonstrated by numerous studies, but its prognostic value in colorectal cancer (CRC) remains unclear. To address this, we developed a mitochondrial-related gene prognostic model using 101 combinations of 10...

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Bibliographic Details

Published in:	Discover Oncology
Main Authors:	Shaoke Wang, Yien Li, Zhihui Wang, Changhui Geng, Peng Chen, Zhengang Li, Chenxu Li, Xuefeng Bai
Format:	Article
Language:	English
Published:	Springer 2025-05-01
Subjects:	Colorectal cancer Mitochondrion Machine learning Prognosis Biomarkers
Online Access:	https://doi.org/10.1007/s12672-025-02462-x