Revolutionizing cancer treatment: the power of bi- and tri-specific T-cell engagers in oncolytic virotherapy

Bi- or tri-specific T cell engagers (BiTE or TriTE) are recombinant bispecific proteins designed to stimulate T-cell immunity directly, bypassing antigen presentation by antigen-presenting cells (APCs). However, these molecules suffer from limitations such as short biological half-life and poor resi...

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الحاوية / القاعدة:	Frontiers in Immunology
المؤلفون الرئيسيون:	Ali Zarezadeh Mehrabadi, Mahdi Tat, Akbar Ghorbani Alvanegh, Fatemeh Roozbahani, Hadi Esmaeili Gouvarchin Ghaleh
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Frontiers Media S.A. 2024-02-01
الموضوعات:	cancer immunotherapy oncolytic viruses bi-specific t cell engagers tri-specific t cell engagers combination therapy
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1343378/full