Enhancement of Neuroglial Extracellular Matrix Formation and Physiological Activity of Dopaminergic Neural Cocultures by Macromolecular Crowding

The neuroglial extracellular matrix (ECM) provides critical support and physiological cues for the proper growth, differentiation, and function of neuronal cells in the brain. However, in most in vitro settings that study neural physiology, cells are grown as monolayers on stiff surfaces that maximi...

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Bibliographic Details

Published in:	Cells
Main Authors:	Andy N. Vo, Srikanya Kundu, Caroline Strong, Olive Jung, Emily Lee, Min Jae Song, Molly E. Boutin, Michael Raghunath, Marc Ferrer
Format:	Article
Language:	English
Published:	MDPI AG 2022-07-01
Subjects:	extracellular matrices macromolecular crowding human iPSC derived astrocyte and dopaminergic neurons drug testing
Online Access:	https://www.mdpi.com/2073-4409/11/14/2131