Association of HbA1c/HDL-C ratio and depression with cardiometabolic multimorbidity in middle-aged and older adults: a nationwide prospective cohort study

BackgroundCardiometabolic multimorbidity (CMM)—the coexistence of two or more cardiometabolic diseases such as diabetes, heart disease, and stroke—poses serious health risks. Depression has recently been recognized as an independent risk factor for CMM. However, the role of the glycosylated hemoglob...

Full description

Bibliographic Details
Published in:	Frontiers in Nutrition
Main Authors:	Jiayang Dong, Aodi Huang, Zhiqiang Zhang, Xinyue Yang, Jiayi Sun, Wenjuan Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	glycosylated hemoglobin A1c high-density lipoprotein cholesterol HbA1c/HDL-C ratio depression cardiometabolic multimorbidity CHARLS
Online Access:	https://www.frontiersin.org/articles/10.3389/fnut.2025.1642243/full

Similar Items

Data-driven analysis of the relationship between the HbA1c/HDL-C ratio and coronary artery calcification: a cross-sectional study
by: Chen Chen, et al.
Published: (2025-08-01)

"SERUM FERRITIN IN TYPE 2 DIABETES MELLITUS AND ITS RELATIONSHIP WITH HbA1c"
by: F. Sharifi Sh. Sazandeh
Published: (2004-06-01)

Association of visit-to-visit HbA1c variability with cardiovascular diseases in type 2 diabetes within or outside the target range of HbA1c
by: Bao Sun, et al.
Published: (2022-11-01)

Significance of HbA1c in Monitoring Diabetes at the Public Hospital, Guyana
by: Rajini Kurup, et al.
Published: (2019-05-01)

Association between HbA1c and dyslipidemia among sample of Iraqi Patients with Type2 DM
by: Ali M. Hami
Published: (2021-10-01)

Correlation Between HbA1C Levels And C-Reactive Protein Levels In Diabetes Mellitus Patients
by: TIMBUL MUJIONO, et al.
Published: (2025-02-01)

Comparison of Two Methods for Measurement of HbA1c in Two University Hospitals of Mashhad
by: Saeid Davari Edalat Panah, et al.
Published: (2015-07-01)

Is HbA1c Predictive for Screening and Diagnosis of Gestational Diabetes Mellitus?
by: Neslihan Yerebasmaz, et al.
Published: (2014-08-01)

Characteristic Analysis of Type 2 Diabetes Mellitus Based on HbA1C
by: Sulistyo Andarmoyo, et al.
Published: (2020-01-01)

Orthostatic Hypotension and its Relationship with HbA1c Levels in Patients with Diabetes Mellitus
by: Deep Bavaria, et al.
Published: (2022-09-01)

The relationship between HbA1c control pattern and atherosclerosis progression of diabetes: a prospective study of Chinese population
by: Kun Li, et al.
Published: (2024-06-01)

The Correlation Between HbA1c and Neuropathy Disability Score in Type 2 Diabetes
by: Ilsa Hunaifi, et al.
Published: (2021-07-01)

HbA1c levels in hemoglobin H disease
by: Pasiri Kerdsinchai, et al.
Published: (2025-09-01)

Joint effect of visit-to-visit variability in LDL-cholesterol, HDL-cholesterol and HbA1c on cardiovascular and total mortality in patients with diabetes
by: Panpan He, et al.
Published: (2022-09-01)

Correlation of HbA1c and Lipids with Obesity in Patients with Type 2 Diabetes in Pakistani Population
by: Hassan Ur Rehman, et al.
Published: (2023-10-01)

HbA1c levels at presentation do not impact the clinical presentation or outcomes in abdominal tuberculosis
by: Jimil Shah, et al.
Published: (2019-01-01)

Correlation between Insulin antibodyand HbA1c in Diabetes Mellitus
by: Joumana Sharad, et al.
Published: (2024-12-01)

HbA1C, proliferative and non-proliferative retinopathy in diabetic patients
by: Faeze Poshtchaman, et al.
Published: (2023-07-01)

Early hip arthroplasty in elderly hip-fracture patients: a perspective from HbA1c
by: Rong-Zhen Xie, et al.
Published: (2025-09-01)

Association between weight loss and HbA1c management in patients with diabetes: a NHANES analysis
by: Zheng Zhang, et al.
Published: (2025-05-01)

Glycated haemoglobin - when can we trust it? Analysis of factors affecting the HbA1c level
by: Marcin Lewicki, et al.
Published: (2018-12-01)

Implicit HbA1c Achieving 87% Accuracy within 90 Days in Non-Invasive Fasting Blood Glucose Measurements Using Photoplethysmography
by: Justin Chu, et al.
Published: (2023-10-01)

Association between the hemoglobin A1c/High-density lipoprotein cholesterol ratio and stroke incidence: a prospective nationwide cohort study in China
by: Chaojuan Huang, et al.
Published: (2025-01-01)

HbA1c levels and breast cancer prognosis in women without diabetes
by: Jonas Busk Holm, et al.
Published: (2025-04-01)

Glycemic control, HbA1c variability, and major cardiovascular adverse outcomes in type 2 diabetes patients with elevated cardiovascular risk: insights from the ACCORD study
by: Junyu Pei, et al.
Published: (2023-10-01)

HUBUNGAN TINGKAT KEPATUHAN MINUM OBAT ANTIDIABETIK ORAL TERHADAP KADAR HEMOGLOBIN TERGLIKASI (HbA1c) PADA PASIEN DIABETES MELITUS TIPE 2
by: Wirawan Adikusuma, et al.
Published: (2017-10-01)

Role of HbA1C level as a diagnostic tool of diabetes and pre-diabetes in middle-aged Bangladeshi population
by: A Begum, et al.
Published: (2015-01-01)

Trends in Quantification of HbA1c Using Electrochemical and Point-of-Care Analyzers
by: Pavan Kumar Mandali, et al.
Published: (2023-02-01)

Improving type 2 diabetes detection among at-risk individuals – comparing the effectiveness of active opportunistic screening using spot capillary-HbA1c testing and venous HbA1c testing: a cluster randomized controlled trial
by: Linda Chan, et al.
Published: (2025-03-01)

The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes
by: Catarina Budyono, et al.
Published: (2016-09-01)

The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes
by: Catarina Budyono, et al.
Published: (2016-09-01)

Machine-Learning-Based Noninvasive In Vivo Estimation of HbA1c Using Photoplethysmography Signals
by: Tae-Ho Kwon, et al.
Published: (2022-04-01)

The role of HbA1c as a diagnostic test for type 2 diabetes mellitus in Bangladesh
by: Md. Matiur Rahman, et al.
Published: (2016-08-01)

Changes of HbA1c variability after the switch to a longer‐acting insulin analog in people with type 1 diabetes
by: Hirotaka Watanabe, et al.
Published: (2023-02-01)

Intensified glycemic control by HbA1c for patients with coronary heart disease and Type 2 diabetes: a review of findings and conclusions
by: Jingyang Chen, et al.
Published: (2023-06-01)

The Effect of HbA<sub>1c</sub> Variability as a Risk Measure for Microangiopathy in Type 1 Diabetes Mellitus
by: Pedro Romero-Aroca, et al.
Published: (2021-06-01)

The HbA1c/HDL-C ratio as a screening indicator of NAFLD in U.S. adults: a cross-sectional NHANES analysis (2017–2020)
by: Ju Wu, et al.
Published: (2025-05-01)

HbA1c, Coronary atheroma progression and cardiovascular outcomes
by: Iryna Dykun, et al.
Published: (2022-03-01)

EFFECT OF MODERATE DOSE OF INHALED BUDESONIDE ON HBA1C IN ASTHMATIC CHILDREN
by: Wasim A Wani, et al.
Published: (2019-03-01)

Can Hba1c Act as A Surrogate Marker for Cardiovascular Risk?
by: Manish B Patel, et al.
Published: (2014-03-01)