The Nuclear Receptor PXR in Chronic Liver Disease
Pregnane X receptor (PXR), a nuclear receptor known for modulating the transcription of drug metabolizing enzymes and transporters (DMETs), such as cytochrome P450 3A4 and P-glycoprotein, is functionally involved in chronic liver diseases of different etiologies. Furthermore, PXR activity relates to...
| Published in: | Cells |
|---|---|
| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-12-01
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| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4409/11/1/61 |