CHD6 eviction of promoter nucleosomes maintains housekeeping transcriptional program in prostate cancer

CHD6, a member of the chromodomain helicase DNA-binding protein family, has been implicated in various diseases and tumors. However, its precise binding model of CHD6 on regulatory functional genes remains poorly understood. In this study, we discovered sharp peaks of CHD6, as the first member of CH...

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Bibliographic Details

Published in:	Molecular Therapy: Nucleic Acids
Main Authors:	Lina Bu, Shaodong Huang, Ziyan Rao, Chenyang Wu, Bryan-Yu Sun, Yanhua Liu, Lin He, Dongyu Zhao
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Subjects:	MT: Bioinformatics CHD6 housekeeping genes histone modifications epigenetics chromatin remodeling
Online Access:	http://www.sciencedirect.com/science/article/pii/S2162253124002841