Inducible Kiss1 knockdown in the hypothalamic arcuate nucleus suppressed pulsatile secretion of luteinizing hormone in male mice

Accumulating evidence suggests that kisspeptin-GPR54 signaling is indispensable for gonadotropin-releasing hormone (GnRH)/gonadotropin secretion and consequent reproductive functions in mammals. Conventional Kiss1 knockout (KO) mice and rats are reported to be infertile. To date, however, no study h...

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Published in:	The Journal of Reproduction and Development
Main Authors:	Shiori MINABE, Sho NAKAMURA, Eri FUKUSHIMA, Marimo SATO, Kana IKEGAMI, Teppei GOTO, Makoto SANBO, Masumi HIRABAYASHI, Junko TOMIKAWA, Takuya IMAMURA, Naoko INOUE, Yoshihisa UENOYAMA, Hiroko TSUKAMURA, Kei-Ichiro MAEDA, Fuko MATSUDA
Format:	Article
Language:	English
Published:	The Society for Reproduction and Development 2020-04-01
Subjects:	adeno-associated virus gonadotropin gonadotropin-releasing hormone kiss1 metastin
Online Access:	https://www.jstage.jst.go.jp/article/jrd/66/4/66_2019-164/_pdf/-char/en