Adaptation of Lactobacillus plantarum to Ampicillin Involves Mechanisms That Maintain Protein Homeostasis

ABSTRACT The widespread use of antibiotics has caused great concern in the biosafety of probiotics. In this study, we conducted a 12-month adaptive laboratory evolution (ALE) experiment to select for antibiotics-adapted Lactobacillus plantarum P-8, a dairy-originated probiotic bacterium. During the...

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Bibliographic Details
Published in:mSystems
Main Authors: Chenxia Cao, Jicheng Wang, Yangshuo Liu, Lai-Yu Kwok, Heping Zhang, Wenyi Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2020-02-01
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Online Access:https://journals.asm.org/doi/10.1128/msystems.00853-19