Modelling Graft-Versus-Host Disease in Mice Using Human Peripheral Blood Mononuclear Cells

Graft-versus-host disease (GvHD) is a significant complication of allogeneic hematopoietic stem cell transplantation. In order to develop new therapeutic approaches, there is a need to recapitulate GvHD effects in pre-clinical, in vivo systems, such as mouse and humanized mouse models. In humanized...

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Bibliographic Details
Published in:Bio-Protocol
Main Authors: Manjurul Haque, Dominic Boardman, Avery Lam, Katerine MacDonald, Lieke Sanderink, Qing Huang, Vivian Fung, Sabine Ivison, Majid Mojibian, Megan Levings
Format: Article
Language:English
Published: Bio-protocol LLC 2022-12-01
Online Access:https://bio-protocol.org/en/bpdetail?id=4566&type=0