Validation of a novel index to assess insulin resistance of adipose tissue lipolytic activity in obese subjects

Insulin resistance in adipose tissue increases the release of free fatty acids into the circulation, which likely contributes to impaired insulin action in liver and skeletal muscle associated with obesity. However, reliable assessment of adipose tissue insulin resistance requires performing a hyper...

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Bibliographic Details

Published in:	Journal of Lipid Research
Main Authors:	Elisa Fabbrini, Faidon Magkos, Caterina Conte, Bettina Mittendorfer, Bruce W. Patterson, Adewole L. Okunade, Samuel Klein
Format:	Article
Language:	English
Published:	Elsevier 2012-02-01
Subjects:	fatty acid kinetics palmitate rate of appearance adipose tissue insulin sensitivity suppression of lipolysis hyperinsulinemic-euglycemic clamp stable isotope tracers
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520407904