Protective IgM-mediated immunity against Vibrio anguillarum in Atlantic cod with evolutionary losses of mhc class II and cd4

The unique adaptive immune system of the Atlantic cod (Gadus morhua), with genetic loss of the mhc class II and cd4, poses questions about the protective role of specific antibodies in this species. We investigate the IgM response against Vibrio anguillarum, a common pathogen in aquaculture. Juvenil...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Alexandra Jonsson, Adrián López-Porras, Simen Foyn Nørstebø, Naomi Croft Guslund, Henning Sørum, Shuo-Wang Qiao, Finn-Eirik Johansen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Subjects:	Atlantic cod Vibrio anguillarum IgM antibodies antibody response adaptive immunity aquaculture
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1579541/full