Potential role of hypoxia in early stages of Hodgkin lymphoma pathogenesis

A unique feature of the germinal center B cell-derived Hodgkin and Reed/Sternberg cells of classical Hodgkin lymphoma is their lost B cell phenotype and the aberrant expression of factors of other hematopoietic cell types, including ID2 and NOTCH1. As cellular dedifferentiation and upregulation of I...

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Bibliographic Details

Published in:	Haematologica
Main Authors:	Frederik Wein, Teresa Otto, Pascal Lambertz, Joachim Fandrey, Martin-Leo Hansmann, Ralf Küppers
Format:	Article
Language:	English
Published:	Ferrata Storti Foundation 2015-10-01
Online Access:	https://haematologica.org/article/view/7526