Destruction of self-derived PAMP via T3SS2 effector VopY to subvert PAMP-triggered immunity mediates Vibrio parahaemolyticus pathogenicity

Summary: Cyclic di-guanosine monophosphate (c-di-GMP) is a unique bacterial second messenger but is hijacked by host cells during bacterial infection as a pathogen-associated molecular pattern (PAMP) to trigger STING-dependent immune responses. Here, we show that upon infection, VopY, an effector of...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Xuan Wu, Lantian Zhou, Chen Ye, Zhenzhong Zha, Chuchu Li, Chao Feng, Yue Zhang, Qian Jin, Jianyi Pan
Format:	Article
Language:	English
Published:	Elsevier 2023-10-01
Subjects:	CP: Microbiology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124723012731