Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activation

The Deleted in liver cancer 1 (Dlc1) gene codes for a Rho GTPase-activating protein that also acts as a tumour suppressor gene. Several studies have consistently found that overexpression leads to excessive cell elongation, cytoskeleton changes and subsequent cell death. However, none of these studi...

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Bibliographic Details
Published in:Biology Open
Main Authors: Mohammad G. Sabbir, Rachelle Dillon, Michael R. A. Mowat
Format: Article
Language:English
Published: The Company of Biologists 2016-04-01
Subjects:
Online Access:http://bio.biologists.org/content/5/4/452