The Autophagy-Lysosomal Pathways and Their Emerging Roles in Modulating Proteostasis in Tumors

In normal physiological condition, the maintenance of cellular proteostasis is a prerequisite for cell growth, functioning, adapting to changing micro-environments, and responding to extracellular stress. Cellular proteostasis is maintained by specific proteostasis networks (PNs) to prevent protein...

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Bibliographic Details

Published in:	Cells
Main Authors:	Zhen Dong, Hongjuan Cui
Format:	Article
Language:	English
Published:	MDPI AG 2018-12-01
Subjects:	autophagy-lysosomal pathways proteostasis protein misfolding aggrephagy tumors aggregates proteostasis networks chaperones
Online Access:	https://www.mdpi.com/2073-4409/8/1/4