Integrated network pharmacology reveals the mechanism of action of Xianlinggubao prescription for inflammation in osteoarthritis

Abstract Background Osteoarthritis (OA), a leading cause of disability worldwide, is characterized by complex interactions between cartilage degradation and synovial inflammation. While NSAIDs are the primary treatment, their prolonged use exacerbates gastrointestinal risks and does not alter diseas...

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Bibliographic Details

Published in:	BMC Complementary Medicine and Therapies
Main Authors:	Jingyi Hou, Yubo Li, Yu Zhang, Ning Yang, Bin Chen, Guiyun Ma, Naiqiang Zhu
Format:	Article
Language:	English
Published:	BMC 2025-05-01
Subjects:	Bioinformatics analysis Hub gene Network pharmacology NF-κB Osteoarthritis Xianlinggubao prescription
Online Access:	https://doi.org/10.1186/s12906-025-04928-5