Estimating the effective sample size in association studies of quantitative traits

AbstractThe effective sample size (ESS) is a metric used to summarize in a single term the amount of correlation in a sample. It is of particular interest when predicting the statistical power of genome-wide association studies (GWAS) based on linear mixed models. Here, we introduce an analytical fo...

Full description

Bibliographic Details
Published in:G3: Genes, Genomes, Genetics
Main Authors: Andrey Ziyatdinov, Jihye Kim, Dmitry Prokopenko, Florian Privé, Fabien Laporte, Po-Ru Loh, Peter Kraft, Hugues Aschard
Format: Article
Language:English
Published: Oxford University Press 2021-03-01
Online Access:https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkab057