Characterization of genetic mutations in hepatitis B virus isolated from HBsAg+/HBcAb+/HBsAb-/HBV DNA + Japanese blood donors

Abstract In Japan, a universal hepatitis B (HB) vaccination was introduced in 2016. Through continuous analysis of HBV DNA mutations, the changes in HBV prevalence before and after the introduction of the universal HB vaccine can be monitored. In this study, we conducted mutational analysis of HBV D...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Ayako Sedohara, Kazuaki Takahashi, Takeya Tsutsumi, Keiko Arai, Fumio Nakahara, Kazuhiko Ikeuchi, Eisuke Adachi, Hiroshi Yotsuyanagi
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Subjects:
Hepatitis b virus
Full-genome sequencing
Precore/core mutation
Immune escape mutation
Core promoter mutation
Online Access:https://doi.org/10.1038/s41598-025-17245-1

Internet

https://doi.org/10.1038/s41598-025-17245-1

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