Changes in Gene Expression Patterns in the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma Under Chemoradiotherapy Depend on Response

Chemoradiotherapy (CRT) is a standard treatment for advanced head and neck squamous cell carcinoma (HNSCC). Unfortunately, not all patients respond to this therapy and require further treatment, either salvage surgery or palliative therapy. The addition of immunotherapy to CRT is currently being inv...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Johannes Doescher, Adrian von Witzleben, Konstantinos Boukas, Stephanie E. Weissinger, Gareth J. Thomas, Simon Laban, Jaya Thomas, Thomas K. Hoffmann, Christian H. Ottensmeier
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-04-01
Subjects:	head and neck squamous cell carcinoma chemoradiotherapy tumor microenvironment tissue resident memory T cells gene set enrichment
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2022.862694/full