BMP-7 modified exosomes derived from synovial mesenchymal stem cells attenuate osteoarthritis by M2 polarization of macrophages

Background: Although the exosomes derived from mesenchymal stem cells (MSCs) display a therapeutic effect on inflammatory diseases, its application on OA has great limitations due to lack of specificity and targeting. The current study aimed to elucidate the potential therapeutic role of bone morpho...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Weixue Sun, Shaozheng Qu, Mingxia Ji, Yanli Sun, Baiqiang Hu
Format:	Article
Language:	English
Published:	Elsevier 2023-09-01
Subjects:	Exosomes Inflammation Macrophage polarization BMP-7 Targeted drug delivery Osteoarthritis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844023071426