Th2-biased immune responses to body migrating Ascaris larvae in primary infection are associated with pathology but not protection

Abstract Helminth infections lead to an overdispersion of the parasites in humans as well as in animals. We asked whether early immune responses against migrating Ascaris larvae are responsible for the unequal distribution of worms in natural host populations and thus investigated a susceptible vers...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Luis E. Elizalde-Velázquez, Josephine Schlosser-Brandenburg, Alexandra Laubschat, Larissa Oser, Arkadi Kundik, Joshua Adjah, Saskia Groenhagen, Anja A. Kühl, Sebastian Rausch, Susanne Hartmann
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Online Access:https://doi.org/10.1038/s41598-024-65281-0