Molecular and cellular mechanisms of developmental synapse elimination in the cerebellum: Involvement of autism spectrum disorder-related genes

Neural circuits are initially created with excessive synapse formation until around birth and undergo massive reorganization until they mature. During postnatal development, necessary synapses strengthen and remain, whereas unnecessary ones are weakened and eventually eliminated. These events, colle...

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Bibliographic Details

Published in:	Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
Main Authors:	Takaki WATANABE, Masanobu KANO
Format:	Article
Language:	English
Published:	The Japan Academy 2024-11-01
Subjects:	cerebellum climbing fiber purkinje cell development synapse elimination autism spectrum disorder
Online Access:	https://www.jstage.jst.go.jp/article/pjab/100/9/100_pjab.100.034/_html/-char/en