Circulating memory PD-1+CD8+ T cells and PD-1+CD8+T/PD-1+CD4+T cell ratio predict response and outcome to immunotherapy in advanced gastric cancer patients

Abstract Background Limited benefit population of immunotherapy makes it urgent to select effective biomarkers for screening appropriate treatment population. Herein, we have investigated the predictive values of circulating CD8+ T cells and CD8+T/CD4+T cell ratio in advanced gastric cancer patients...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Cancer Cell International
المؤلفون الرئيسيون:	Jiang Liu, Degan Liu, Guangyin Hu, Jingjing Wang, Dadong Chen, Chuanjun Song, Yin Cai, Chentong Zhai, Wenjing Xu
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	BMC 2023-11-01
الموضوعات:	Gastric cancer Immunotherapy Immune checkpoint inhibitors Memory CD8+ T cells CD8+T/CD4+T cell ratio Predictive biomarkers
الوصول للمادة أونلاين:	https://doi.org/10.1186/s12935-023-03137-9