Long-lasting and fast methylglyoxal-scavenging peptide CycK(Myr)R4E alleviates chronic pain in type 2 diabetic mice

Abstract. Introduction:. Pathological levels of methylglyoxal (MG), a reactive dicarbonyl product of glucose, contribute to major neurological complications associated with type II diabetes, including chronic neuropathic pain. Strategies to target elevated MG have included small molecule MG scavenge...

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Bibliographic Details

Published in:	PAIN Reports
Main Authors:	Paramita Basu, Diogo F. S. Santos, Nina Gakii, Margaret R. Gralinski, Ryan B. Griggs, Sebastian Brings, Thomas Fleming, Keiichiro Susuki, Bradley K. Taylor
Format:	Article
Language:	English
Published:	Wolters Kluwer 2025-10-01
Online Access:	http://journals.lww.com/painrpts/fulltext/10.1097/PR9.0000000000001312