An NBD derivative of the selective rat toxicant norbormide as a new probe for living cell imaging.

Norbormide (NRB) is a unique compound that acts directly on rat vascular myocytes to trigger a contractile process, through an as yet unknown mechanism, which results in the selective contraction of rat peripheral arteries. To gain insight into the mechanisms involved in NRB rat-selective activity,...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Claudio D'amore, Genny Orso, Fabio Fusi, Mario Angelo Pagano, Giovanni Miotto, Alessia Forgiarini, Sara De Martin, Giulia Castellani, Giovanni Ribaudo, David Rennison, Margaret Anne Brimble, Brian Hopkins, Alessandro Ferrarese, Sergio Bova
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-09-01
Subjects:	Fluorescent probes Norbormide LX2 cells Sulphonylurea Receptors ER Tracker
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00315/full