GTSE1 is possibly involved in the DNA damage repair and cisplatin resistance in osteosarcoma

Abstract Background G2 and S phase-expressed-1 (GTSE1) negatively regulates the tumor-suppressive protein p53 and is potentially correlated with chemoresistance of cancer cells. This study aims to explore the effect of GTSE1 on the DNA damage repair and cisplatin (CDDP) resistance in osteosarcoma (O...

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Bibliographic Details
Published in:Journal of Orthopaedic Surgery and Research
Main Authors: Chaofan Xie, Wei Xiang, Huiyong Shen, Jingnan Shen
Format: Article
Language:English
Published: BMC 2021-12-01
Subjects:
Osteosarcoma
GTSE1
DNA repair
Cisplatin
Drug resistance
Online Access:https://doi.org/10.1186/s13018-021-02859-8

Internet

https://doi.org/10.1186/s13018-021-02859-8

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