Semi-Automated Recording of Facial Sensitivity in Rat Demonstrates Antinociceptive Effects of the Anti-CGRP Antibody Fremanezumab

Migraine pain is frequently accompanied by cranial hyperalgesia and allodynia. Calcitonin gene-related peptide (CGRP) is implicated in migraine pathophysiology but its role in facial hypersensitivity is not entirely clear. In this study, we investigated if the anti-CGRP monoclonal antibody fremanezu...

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Bibliographic Details
Published in:Neurology International
Main Authors: Nicola Benedicter, Karl Messlinger, Birgit Vogler, Kimberly D. Mackenzie, Jennifer Stratton, Nadine Friedrich, Mária Dux
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Subjects:
fremanezumab
monoclonal antibody
behavioral model
mechanical sensitivity
thermal sensitivity
calcitonin gene-related peptide
Online Access:https://www.mdpi.com/2035-8377/15/2/39

Internet

https://www.mdpi.com/2035-8377/15/2/39

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