Neuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation

During Drosophila and vertebrate brain development, the conserved transcription factor Prospero/Prox1 is an important regulator of the transition between proliferation and differentiation. Prospero level is low in neural stem cells and their immediate progeny, but is upregulated in larval neurons an...

Full description

Bibliographic Details

Published in:	Biology Open
Main Authors:	Tamsin J. Samuels, Yoav Arava, Aino I. Järvelin, Francesca Robertson, Jeffrey Y. Lee, Lu Yang, Ching-Po Yang, Tzumin Lee, David Ish-Horowicz, Ilan Davis
Format:	Article
Language:	English
Published:	The Company of Biologists 2020-05-01
Subjects:	prospero syncrip mrna stability neuroblast post-transcriptional regulation
Online Access:	http://bio.biologists.org/content/9/5/bio049684