A long-term mouse testis organ culture system to identify germ cell damage induced by chemotherapy

We previously developed the acrosin-green fluorescent protein (GFP) transgenic neonatal mouse organ culture system for rapid and accurate assessment of testicular toxicity. This system effectively evaluates drug-induced toxicity in male germ cells before meiotic entry but cannot assess post-meiotic...

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Bibliographic Details

Published in:	Current Research in Toxicology
Main Authors:	Satoshi Yokota, Kiyoshi Hashimoto, Takuya Sato, Koichi Uemura, Kazuhide Makiyama, Takuya Nishimura, Satoshi Kitajima, Takehiko Ogawa
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Subjects:	Acrosin-GFP mouse Testis organ culture Testicular toxicity Recovery Cisplatin
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666027X25000143