Analysis of the effect of HDAC inhibitors on the formation of the HIV reservoir

ABSTRACT The HIV reservoir is more dynamic than previously thought with around 70% of the latent reservoir originating from viruses circulating within 1 year of the initiation of antiretroviral therapy (ART). In an ex vivo model system of HIV latency, it was reported that early exposure to class I h...

Full description

Bibliographic Details

Published in:	mBio
Main Authors:	Lijun Ling, Manse Kim, Andrew Soper, Martina Kovarova, Rae Ann Spagnuolo, Nurjahan Begum, Jennifer Kirchherr, Nancie Archin, Diana Battaglia, Dave Cleveland, Angela Wahl, David M. Margolis, Edward P. Browne, J. Victor Garcia
Format:	Article
Language:	English
Published:	American Society for Microbiology 2024-09-01
Subjects:	histone deacetylase inhibitors human immunodeficiency virus reservoir latency
Online Access:	https://journals.asm.org/doi/10.1128/mbio.01632-24