Cisplatin-Induced Ototoxicity in Rats Is Driven by RIP3-Dependent Necroptosis

Cisplatin-induced early-onset ototoxicity is linked to hearing loss. The mechanism by which cisplatin causes ototoxicity remains unclear. The purpose of this study was to identify the involvement of receptor-interacting protein kinase (RIP)3-dependent necroptosis in cisplatin-induced ototoxicity in...

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Bibliographic Details
Published in:Cells
Main Authors: Mi-Jin Choi, Hyunsook Kang, Yun Yeong Lee, Oak-Sung Choo, Jeong Hun Jang, Sung-Hee Park, Jong-Seok Moon, Seong Jun Choi, Yun-Hoon Choung
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Subjects:
necroptosis
cisplatin
ototoxicity
organ of Corti
spiral ganglion neuron
Online Access:https://www.mdpi.com/2073-4409/8/5/409

Internet

https://www.mdpi.com/2073-4409/8/5/409

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