Synthesis and Characterization of Novel 1,3-Thiazole and 2-Amino-1,3,4-Thiadiazole Derivatives

Thiosemicarbazone derivatives 3a–e were synthesized by the reaction of various aldehydes 1a–e with 4-methyl thiosemicarbazide 2 in 78% to 90% yield. Then, the thiazole moieties of the target materials 5a–e were obtained in high yields (71–93%) using the Hantzsch reaction utilizing thiosemicarbazone...

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Bibliographic Details

Published in:	Macedonian Journal of Chemistry and Chemical Engineering
Main Authors:	Mustafa Er, Ayşe Şahin, Hakan Tahtacı
Format:	Article
Language:	English
Published:	Society of Chemists and Technologists of Macedonia 2014-11-01
Subjects:	thiosemicarbazone 1,3-thiazole 2-amino-1,3,4-thiadiazole hantzsch reaction
Online Access:	https://mjcce.org.mk/index.php/MJCCE/article/view/522