The current landscape of CAR T-cell therapy for solid tumors: Mechanisms, research progress, challenges, and counterstrategies

The successful outcomes of chimeric antigen receptor (CAR) T-cell therapy in treating hematologic cancers have increased the previously unprecedented excitement to use this innovative approach in treating various forms of human cancers. Although researchers have put a lot of work into maximizing the...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Amin Daei Sorkhabi, Leila Mohamed Khosroshahi, Aila Sarkesh, Amirhossein Mardi, Ali Aghebati-Maleki, Leili Aghebati-Maleki, Behzad Baradaran
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	chimeric antigen receptor CAR T-cell immunotherapy solid tumors challenges clinical trials
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1113882/full