Exploration of multifaceted molecular mechanism of angiotensin-converting enzyme 2 (ACE2) in pathogenesis of various diseases

Angiotensin converting enzyme 2 (ACE2) is a homolog of ACE (a transmembrane bound dipeptidyl peptidase enzyme). ACE2 converts angiotensinogen to the heptapeptide angiotensin-(1–7). ACE2 and its product, angiotensin-(1–7), have counteracting effects against the adverse actions of other members of ren...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Aditi D. Kunvariya, Shivani A. Dave, Zeal J. Modi, Paresh K. Patel, Sneha R. Sagar
Format:	Article
Language:	English
Published:	Elsevier 2023-05-01
Subjects:	Angiotensin-converting enzyme 2 Angiotensin II Renin-angiotensin system SARS-CoV-2 Cancer Neurodegenerative diseases
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844023028517