Exploration of multifaceted molecular mechanism of angiotensin-converting enzyme 2 (ACE2) in pathogenesis of various diseases

Angiotensin converting enzyme 2 (ACE2) is a homolog of ACE (a transmembrane bound dipeptidyl peptidase enzyme). ACE2 converts angiotensinogen to the heptapeptide angiotensin-(1–7). ACE2 and its product, angiotensin-(1–7), have counteracting effects against the adverse actions of other members of ren...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Heliyon
المؤلفون الرئيسيون:	Aditi D. Kunvariya, Shivani A. Dave, Zeal J. Modi, Paresh K. Patel, Sneha R. Sagar
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Elsevier 2023-05-01
الموضوعات:	Angiotensin-converting enzyme 2 Angiotensin II Renin-angiotensin system SARS-CoV-2 Cancer Neurodegenerative diseases
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2405844023028517

مواد مشابهة

The role of renin-angiotensin system and angiotensin-converting enzyme 2 (ACE2) in the development and course of viral infection COVID-19 in patients with diabetes mellitus
حسب: O. K. Vikulova, وآخرون
منشور في: (2020-08-01)

The role of the classical renin–angiotensin system and angiotensin-converting enzyme 2/Ang(1–7)/Mas axis in pulmonary fibrosis
حسب: Changhui Lang, وآخرون
منشور في: (2025-07-01)

Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors
حسب: Daniel eClayton, وآخرون
منشور في: (2015-01-01)

Effect of angiotensin receptor blockers and angiotensin‐converting enzyme 2 on plasma equilibrium angiotensin peptide concentrations in cats with heart disease
حسب: Terry Huh, وآخرون
منشور في: (2021-01-01)

Progress of angiotensin converting enzyme 2 in cardiovascular diseases
حسب: JIAO Xiao-lu, QIN Yan-wen
منشور في: (2020-05-01)

Urinary Angiotensin Converting Enzyme 2 Increases in Patients With Type 2 Diabetic Mellitus
حسب: Yaoxian Liang, وآخرون
منشور في: (2015-03-01)

Angiotensin II and Angiotensin Receptors 1 and 2—Multifunctional System in Cells Biology, What Do We Know?
حسب: Maksymilian Ziaja, وآخرون
منشور في: (2021-02-01)

The Impact of Angiotensin-Converting Enzyme-2/Angiotensin 1-7 Axis in Establishing Severe COVID-19 Consequences
حسب: Minela Aida Maranduca, وآخرون
منشور في: (2022-09-01)

Lack of association between angiotensin-converting enzyme (ACE) genotype and essential hypertension in Peruvian older people
حسب: Teodoro J. Oscanoa, وآخرون
منشور في: (2020-09-01)

The Renin–Angiotensin System Modulates SARS-CoV-2 Entry via ACE2 Receptor
حسب: Sophia Gagliardi, وآخرون
منشور في: (2025-07-01)

Role of Angiotensin Type 2 Receptor on Nitric Oxide Production Response to Angiotensin II Administration in Ovariectomised Rats Treated with Estradiol
حسب: Tahereh Safari, وآخرون
منشور في: (2014-01-01)

Differential Roles of Angiotensin A and Alamandine in Parkinson's Disease: A Therapeutic Perspective on Nonclassical RAS Pathways
حسب: Ghadah H. Alshehri, وآخرون
منشور في: (2025-08-01)

Severity of SARS-COV-2 infection and angiotensin converting enzyme inhibitors and angiotensin receptor blockers: a meta-analysis
حسب: Teodoro J. Oscanoa, وآخرون
منشور في: (2020-09-01)

Renin-Angiotensin System: A Review of Historical Perspectives
حسب: Olga Kovalyova, وآخرون
منشور في: (2023-05-01)

From gene to protein - experimental and clinical studies of ACE2 in blood pressure control and arterial hypertension
حسب: Sheila K Patel, وآخرون
منشور في: (2014-06-01)

Clinical usefulness of serum angiotensin converting enzyme in silicosis
حسب: J. Blanco-Pérez, وآخرون
منشور في: (2024-07-01)

Relevance Of Angiotensin Converting Enzyme Gene Polymorphism 1978124 With Hypertension In Type 2 Diabetes Mellitus
حسب: Shaimaa Addai Hummady, وآخرون
منشور في: (2024-12-01)

Renin–angiotensin system inhibition in COVID-19 patients: Friend or foe?
حسب: Bilgehan Karadağ
منشور في: (2020-07-01)

Role of the Uteroplacental Renin–Angiotensin System in Placental Development and Function, and Its Implication in the Preeclampsia Pathogenesis
حسب: Lucile Yart, وآخرون
منشور في: (2021-09-01)

RENIN-ANGIOTENSIN SYSTEM IN REGULATION OF HEMATOPOIESIS
حسب: M. L. Kanaeva, وآخرون
منشور في: (2018-02-01)

The Effect of Hydroalcoholic Seed Extract of Securigera Securidaca on the Hepatic Renin-Angiotensin System in the Streptozotocin-Induced Diabetic Animal Model
حسب: Bahar Kiani, وآخرون
منشور في: (2022-04-01)

Angiotensins and rheumatoid arthritis
حسب: N. M. Savushkina, وآخرون
منشور في: (2019-01-01)

The clinical relevance of local renin angiotensin systems
حسب: Duncan John Campbell
منشور في: (2014-07-01)

The renin-angiotensin system and its blockers
حسب: Igić Rajko, وآخرون
منشور في: (2014-01-01)

Renin Is Essential for Angiotensin II Formation in the Brain
حسب: André F. Rodrigues, وآخرون
منشور في: (2024-11-01)

Evaluation of myocardial classic and alternative pathways of the renin-angiotensin system in cholestasis-induced cardiac injury: A time-course experimental study in rats
حسب: Azadeh Khalili, وآخرون
منشور في: (2025-11-01)

Comparison of angiotensin converting enzyme 1 levels to the grading of knee osteoarthritis
حسب: Fidelia Elvira Da Costa Rao, وآخرون
منشور في: (2024-06-01)

Utility of angiotensin-converting enzyme activity in aqueous humor in the diagnosis of ocular sarcoidosis
حسب: Violeta Mihailovic-Vucinic, وآخرون
منشور في: (2017-01-01)

Angiotensin-Converting Enzyme 2 (ACE2) in the Context of Respiratory Diseases and Its Importance in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
حسب: Enrique Ambrocio-Ortiz, وآخرون
منشور في: (2021-08-01)

Effect of the renin-angiotensin system on the exacerbation of adrenal glucocorticoid steroidogenesis in diabetic mice: Role of angiotensin-II type 2 receptor
حسب: Amanda da Silva Chaves, وآخرون
منشور في: (2022-11-01)

Physiopathology of the Brain Renin-Angiotensin System
حسب: Cristina Cueto-Ureña, وآخرون
منشور في: (2025-08-01)

The systemic angiotensin-II role in the development of retinopathy of prematurity
حسب: N. A. Osipova, وآخرون
منشور في: (2023-07-01)

The Effects of Angiotensin II or Angiotensin 1-7 on Rat Pial Microcirculation during Hypoperfusion and Reperfusion Injury: Role of Redox Stress
حسب: Dominga Lapi, وآخرون
منشور في: (2021-12-01)

Duration of rheumatoid arthritis changes blood levels of angiotensin and aldosterone
حسب: Boris A. Rebrov, وآخرون
منشور في: (2023-12-01)

Potassium Intake Prevents the Induction of the Renin-Angiotensin System and Increases Medullary ACE2 and COX-2 in the Kidneys of Angiotensin II-Dependent Hypertensive Rats
حسب: Alexis A. Gonzalez, وآخرون
منشور في: (2019-10-01)

Therapeutic targets of renin-angiotensin system in ocular disorders
حسب: Rajesh Choudhary, وآخرون
منشور في: (2017-03-01)

The Role of Renin–Angiotensin System in Diabetic Cardiomyopathy: A Narrative Review
حسب: João Pedro Thimotheo Batista, وآخرون
منشور في: (2023-07-01)

Age-related reduction in brain ACE-2 is not exacerbated by Alzheimer’s disease pathology in mouse models of Alzheimer’s disease
حسب: Robert MacLachlan, وآخرون
منشور في: (2023-01-01)

Response of cultured primary gingival and periodontal ligament cells to angiotensin II and IL1β challenges
حسب: Thais Francini GARBIERI, وآخرون
منشور في: (2025-09-01)

Impact of Hypertension and Physical Fitness on SARS-COV-2 and related Consequences. (Possible mechanisms with focusing on ACE2)
حسب: Mehdi Kushkestani, وآخرون
منشور في: (2022-01-01)