Effect of dapagliflozin on eGFR slope in IgA nephropathy based on renal pathological assessment using image analysis software

Introduction: Studies have examined the effect of dapagliflozin, a sodium-glucose co-transporter-2 (SGLT2) inhibitor, on chronic kidney disease (CKD), including immunoglobulin A nephropathy (IgAN). Dapagliflozin decreases albuminuria and slows the decline in estimated glomerular filtration rate (eGF...

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Bibliographic Details

Published in:	Metabolism Open
Main Authors:	Akira Mima, Takahiro Nakamoto, Keishi Matsumoto, Yuta Saito, Takaaki Morikawa, Shinji Lee
Format:	Article
Language:	English
Published:	Elsevier 2025-12-01
Subjects:	Immunoglobulin A nephropathy Dapagliflozin Mesangial matrix fraction Image-J Estimate glomerular filtration rate slope decline Proteinuria
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589936825000489