Reduced Tie2 in Microvascular Endothelial Cells Is Associated with Organ-Specific Adhesion Molecule Expression in Murine Health and Endotoxemia

Endothelial cells (ECs) in the microvasculature in organs are active participants in the pathophysiology of sepsis. Tyrosine protein kinase receptor Tie2 (Tek; Tunica interna Endothelial cell Kinase) is thought to play a role in their inflammatory response, yet data are inconclusive. We investigated...

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Bibliographic Details

Published in:	Cells
Main Authors:	Peter J. Zwiers, Jacqueline P. F. E. Lucas, Rianne M. Jongman, Matijs van Meurs, Eliane R. Popa, Grietje Molema
Format:	Article
Language:	English
Published:	MDPI AG 2023-07-01
Subjects:	adhesion molecules endothelial cells endothelial heterogeneity endotoxemia E-selectin inflammation
Online Access:	https://www.mdpi.com/2073-4409/12/14/1850