Sex-specific cardiovascular adaptations to simulated microgravity in Sprague-Dawley rats

Abstract Men and women have different cardiovascular responses to spaceflight; however, few studies have focused on direct comparisons between sexes. We investigated the mechanisms of aortic stiffening in socially and sexually mature 20-week-old male and female Sprague Dawley (SD) rats exposed to hi...

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Bibliographic Details

Published in:	npj Microgravity
Main Authors:	Ebrahim Elsangeedy, Dina N. Yamaleyeva, Nicholas P. Edenhoffer, Allyson Deak, Anna Soloshenko, Jonathan Ray, Xuming Sun, Omar H. Shaltout, Nildris Cruz-Diaz, Brian Westwood, Daniel Kim-Shapiro, Debra I. Diz, Shay Soker, Victor M. Pulgar, April Ronca, Jeffrey S. Willey, Liliya M. Yamaleyeva
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-12-01
Online Access:	https://doi.org/10.1038/s41526-024-00450-z