Molecular and Functional Diversity of Distinct Subpopulations of the Stressed Insulin-Secreting Cell's Vesiculome

Beta cell failure and apoptosis following islet inflammation have been associated with autoimmune type 1 diabetes pathogenesis. As conveyors of biological active material, extracellular vesicles (EV) act as mediators in communication with immune effectors fostering the idea that EV from inflamed bet...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Khem Raj Giri, Laurence de Beaurepaire, Dominique Jegou, Margot Lavy, Mathilde Mosser, Aurelien Dupont, Romain Fleurisson, Laurence Dubreil, Mayeul Collot, Peter Van Endert, Jean-Marie Bach, Gregoire Mignot, Steffi Bosch
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-09-01
Subjects:	type 1 diabetes extracellular vesicles apoptotic bodies microvesicles exosomes microRNA
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2020.01814/full