USP29 Deubiquitinates SETD8 and Regulates DNA Damage-Induced H4K20 Monomethylation and 53BP1 Focus Formation

SETD8 is a histone methyltransferase that plays pivotal roles in several cellular functions, including transcriptional regulation, cell cycle progression, and genome maintenance. SETD8 regulates the recruitment of 53BP1 to sites of DNA damage by controlling histone H4K20 methylation. Moreover, SETD8...

詳細記述

書誌詳細
出版年:Cells
主要な著者: Yeray Hernández-Reyes, María Cristina Paz-Cabrera, Raimundo Freire, Veronique A. J. Smits
フォーマット: 論文
言語:英語
出版事項: MDPI AG 2022-08-01
主題:
オンライン・アクセス:https://www.mdpi.com/2073-4409/11/16/2492