A chemical genetic screen reveals a role for proteostasis in capsule and biofilm formation by Cryptococcus neoformans

Pathogenic microorganisms employ specialized virulence factors to cause disease. Biofilm formation and the production of a polysaccharide capsule are two important virulence factors in Cryptococcus neoformans, the fungal pathogen that causes meningoencephalitis. Here, we show that the bipolar disord...

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Bibliographic Details

Published in:	Microbial Cell
Main Authors:	François L. Mayer, Eddy Sánchez-León, James W. Kronstad
Format:	Article
Language:	English
Published:	Shared Science Publishers OG 2018-10-01
Subjects:	Cryptococcus neoformans lithium proteostasis capsule biofilm
Online Access:	http://microbialcell.com/researcharticles/a-chemical-genetic-screen-reveals-a-role-for-proteostasis-in-capsule-and-biofilm-formation-by-cryptococcus-neoformans/