Overcoming Tumor Resistance to Oncolyticvaccinia Virus with Anti-PD-1-Based Combination Therapy by Inducing Antitumor Immunity in the Tumor Microenvironment

The tumor microenvironment (TME) comprises different types of immune cells, which limit the therapeutic efficacy of most drugs. Although oncolytic virotherapy (OVT) boosts antitumor immunity via enhanced infiltration of tumor-infiltrated lymphocytes (TILs), immune checkpoints on the surface of tumor...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Vaccines
المؤلفون الرئيسيون: So Young Yoo, Narayanasamy Badrinath, Su-Nam Jeong, Hyun Young Woo, Jeong Heo
التنسيق: مقال
اللغة:الإنجليزية
منشور في: MDPI AG 2020-06-01
الموضوعات:
oncolytic virotherapy
immunotherapy
tumor microenvironment
vaccinia virus
immune checkpoints
الوصول للمادة أونلاين:https://www.mdpi.com/2076-393X/8/2/321

الانترنت

https://www.mdpi.com/2076-393X/8/2/321

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