Relationships and Mendelian Randomization of Gut Microbe-Derived Metabolites with Metabolic Syndrome Traits in the METSIM Cohort

The role of gut microbe-derived metabolites in the development of metabolic syndrome (MetS) remains unclear. This study aimed to evaluate the associations of gut microbe-derived metabolites and MetS traits in the cross-sectional Metabolic Syndrome In Men (METSIM) study. The sample included 10,194 ra...

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Bibliographic Details

Published in:	Metabolites
Main Authors:	Sahereh Mirzaei, Holli A. DeVon, Rita M. Cantor, Arjen J. Cupido, Calvin Pan, Sung Min Ha, Lilian Fernandes Silva, James R. Hilser, Jaana Hartiala, Hooman Allayee, Federico E. Rey, Markku Laakso, Aldons J. Lusis
Format:	Article
Language:	English
Published:	MDPI AG 2024-03-01
Subjects:	metabolic syndrome gut microbes gut metabolites insulin resistance Mendelian randomization GWAS
Online Access:	https://www.mdpi.com/2218-1989/14/3/174