Novel PiuC, PirA, and PiuA mutations leading to in vivo cefiderocol resistance progression in IMP-16- and KPC-2-producing Pseudomonas aeruginosa from a leukemic patient

ABSTRACT Pseudomonas aeruginosa is an opportunistic pathogen capable of causing severe infections in immunocompromised individuals, who often require prolonged antibiotic therapy. The emergence of carbapenemase-producing P. aeruginosa has further complicated the management of nosocomial infections,...

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Bibliographic Details

Published in:	Microbiology Spectrum
Main Authors:	Joaquim Viñes, Sabina Herrera, Andrea Vergara, Ignasi Roca, Jordi Vila, Tommaso Francesco Aiello, José Antonio Martínez, Ana del Río, Carlos Lopera, Carolina Garcia-Vidal, Climent Casals-Pascual, Àlex Soriano, Cristina Pitart
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-03-01
Subjects:	Pseudomonas aeruginosa carbapenem-resistant cefiderocol PiuA PiuC PirA
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.01928-24